Should Favipiravir be Used as an Additional Drug in Case of Severe Animal Bites on the Face Especially into the Eyes/ Lips or Aerosol Exposure to Rabies Virus to Prevent Rabies PEP Failures?

Rabies is a zoonotic viral disease that affects the central nervous system leading to respiratory or cardiac failure. Dogs are major source of rabies infection in human beings. 100% fatal but largely preventable if proper and timely Post-Exposure Prophylaxis (PEP) availed form immediate wound wash with soap water injections vaccine immunoglobulins, first week being most important. Here we describe four cases PEP failure despite complete prophylaxis Immunoglobulins (RIG) over past year Himachal Pradesh. All failures were due suspected rabid dog bites on face, especially cheeks, lips, eyes where infiltration RIG may not have been possible We, after extensive research discussion, opinion such situations, add another viricidal oral drug favipiravir along could help prevent situations into wounds difficult achieve. DOI: https://doi.org/10.24321/2349.7181.202211 How cite this article:Bharti OK, Bansal A, Mehta U. Should Favipiravir be Used as an Additional Drug Case Severe Animal Bites Face Especially Eyes/ Lips Aerosol Exposure Virus Prevent Failures? J Adv Res Med. 2022;9(2):27-30.